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we hope this can be a starting point to think about GSH and promote more research on its potential future application in SD or in other inflammatory skin diseases

Transcription factor binding site analysis revealed that hypermethylated sites associated with disease activity were enriched for binding sites of two repressive transcription factors, EZH2 and SUZ12

As a result, mitochondria become increasingly inefficient, producing more ROS and RNS, perpetuating neuronal injury, microglial activation, and chronic inflammation