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51-53 In 2009 and 2011, the Consumer Product Safety Commission began requiring lower lead levels in childrens products (as of 2011, allowing less than 100 ppm [parts per million] of lead in accessible parts of childrens products with some exceptions) 54

Importantly, as the chief brain source of APOE, astrocytes, especially those expressing the APOE4 allele, promote A aggregation, tau pathologies, BBB breakdown, and cerebrovascular dysfunctions (Wang M