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Abbreviations 12-HHTrE: 12-Hydroxyheptadecatrienoic acid 15-d-PGJ 2 : 15-Deoxy-12,14-PGJ2 20-COOH-LTB 4 : 20-Carboxy-LTB4 20-OH-LTB 4 : 20-Hydroxy-leukotriene B4 4-HNE: 4-Hydroxynonenal 6-keto PGF 1 : 6-Ketoprostaglandin F1 AA: Arachidonic acid AAPC: Alkylacylglycerophosphocholines ACD: Allergic contact dermatitis AD: Atopic dermatitis AGA: Androgenetic alopecia AHR: Aryl hydrocarbon receptor AP-1: Activator protein 1 AQP3: Aquaporin-3 AR: Androgen receptor ARCI: Autosomal recessive congenital ichthyosis AVX001: 1-Octadeca-2,6,9,12,15-pentaenylsulfanyl-propan-2-one BAX: Bcl-2-associated X protein Bcl-2: B-cell lymphoma 2 BLT1: Leukotriene B4 receptor 1 BLT2: Leukotriene B4 receptor 2 cAMP: Cyclic adenosine monophosphate CCD 1112Sk: Human fibroblasts CD206: Mannose receptor C type 1 CD25: CD25 T lymphocytes CD4: CD4 T lymphocytes Cer: Ceramides CHS: Chronic hypersensitivity contact dermatitis CL: Cardiolipins CLDN4: Claudin 4 COXs: Cyclooxygenases cPLA2: Cytosolic calcium dependent phospholipase A2 CREB: CAMP response element-binding protein CRL2310: Human immortalized keratinocytes CDD 1102 KERTr CXCL1: Chemokine (C-X-C motif) ligand 1 CXCL2: Chemokine (C-X-C motif) ligand 2 CXCR2: Motif chemokine receptor 2 cyPGs: Cyclopentenone prostaglandins CYPs P450: Cytochromes P450 CysLT1: Cysteinyl leukotriene receptor 1 CysLT2: Cysteinyl leukotriene receptor 2 cys-LTs: Cysteinyl leukotrienes DAG: 1,2-Diacylglycerol DAGL: Diacylglycerol lipase DCs: Dendritic cells DHA: Docosahexaenoic acid DHETs: Dihydroxyeicosatrienoic acids DHS: Hydroxyeicosanoid dehydrogenases DHSM: Dihydrosphingomyelins DiHETEs: Dihydroxyeicosatetraenoic acids DMBA/TPA: 9,10-Dimethylbenz(a)anthracene/12-O-tetradecanoylphorbol-13-acetate DP1: Prostaglandin D2 receptor 1 DP2: Prostaglandin D2 receptor 2 e12-LOX: Epidermal-type 12-lipoxygenase EETs: Epoxyeicosatrienoic acids EGFR: Epidermal growth factor receptor EHS: Epoxide hydrolases EP1: Prostaglandin E2 receptor 1 EP2: Prostaglandin E2 receptor 2 EP3: Prostaglandin E2 receptor 3 EP4: Prostaglandin E2 receptor 4 EPA: Eicosapentaenoic acid Epla: Plasmalogen ethanolamines ERK1/2: Extracellular signal regulated kinase 1/2 EXA 4 : Eoxin A4 EXC 4 : Eoxin C4 EXD 4 : Eoxin D4 EXE 4 : Eoxin E4 FAAH: Fatty acid amide hydrolase FP: Prostaglandin F receptor GM22251: Primary human keratinocytes GPL: Phosphoglycerides GPx: Glutathione peroxidase GSH: Glutathione HaCaT: Human immortalized keratinocytes hBD-3: -Defensin 3 hDPCs: Human dermal papilla cells HETEs: Hydroxy-eicosatetraenoic acids HPEK: Human primary epidermal keratinocytes HpETEs: Hydroperoxyeicosatetraenoic acids HXA 3 : Hepoxilin A3 HXB 3 : Hepoxilin B3 ICAM1: Intercellular adhesion molecule 1 IL-1: Interleukin 1 IL-17A: Interleukin 17A IL-17F: Interleukin 17F IL-1: Interleukin 1 IL-22: Interleukin 22 IL-23: Interleukin 23 IL-31: Interleukin 31 IL-6: Interleukin 6 IMQ: Imiquimod IP: Prostaglandin I2 receptor IP3: Inositol-1,4,5-triphosphate iPLA2: Cytosolic calcium independent phospholipase A2 IsoFS: Isofurans IsoLG: Isolevuglandins IsoP: Isoprostanes IsoTX: Isothromboxanes l12-LOX: Leukocyte-type 12lipoxygenase LA: Linoleic acid LCMS/MS: Liquid chromatography with tandem mass spectrometry LOXs: Lipoxygenases LPA: Lysophosphatidic acid LPC: Lysophosphatidylcholines LPP: Lipid-phosphate phosphatase LTA 4 : Leukotriene A4 LTA 4 H: LTA 4 hydrolase LTB 4 : Leukotriene B4 LTC 4 : Leukotriene C4 LTC 4 S: LTC 4 synthase LTD 4 : Leukotriene D4 LTE 4 : Leukotriene E4 LXA 4 : Lipoxin A4 LXB 4 : Lipoxin B4 MAG: Monoacylglycerol MAGL: Monoacylglycerol lipase MAPK: Mitogen-activated protein kinase MDA: Malondialdehyde MDCs: Macrophage - derived chemokine MIP-2: Macrophage inflammatory protein 2 MMP-1: Extracellular matrix metalloproteinase 1 MMP-2: Extracellular matrix metalloproteinase 2 MPEK: Murine primary epidermal keratinocytes MRSA: Methicillin-resistant Staphylococcus aureus NAC: N-acetylcysteine NAEs: N-acyl ethanolamines NFAT: Nuclear factor of activated T cells NHDF: Human dermal fibroblasts NHEK: Normal human epidermal keratinocytes NIH3T3: Murine fibroblasts OSM: Oncostatin M oxo-ETEs: Oxo-eicosatetraenoic acids p12-LOX: Platelet-type 12-lipoxygenase p38 MAPK: P38 mitogen-activated protein kinases PA: Phosphatidic acid p-Akt: Phosphorylated protein kinase B PAM212: Murine keratinocytes PAR-2: Proteinase-activated receptor 2 PC: Phosphatidylcholines PE: Phosphatidylethanolamines PG: Phosphatidylglycerols PGA 2 : Prostaglandin A2 PGB 2 : Prostaglandin B2 PGD 2 : Prostaglandin D2 PGE 2 : Prostaglandin E2 PGG 2 : Prostaglandin G2 PGH 2 : Prostaglandin H2 PGI 2 : Prostaglandin I2 PGJ 2 : Prostaglandin J2 p-GSK3: Phosphorylated glycogen synthase kinase 3 PGXS: Prostaglandin synthase PH: Pleckstrin homology PI: Phosphatidylinositols PIP2: 4,5-Bisphosphate phosphatidylinositol PKA: Cyclic AMP-dependent protein kinase PKC: Protein kinase C zeta PLA1: Phospholipase A1 PLA2: Phospholipase A2 PLB: Phospholipase B PLC: Phospholipase C PLD: Phospholipase D PLD1: Phospholipase D1 PLD2: Phospholipase D2 P-LPE: Plasmalogen-type lysoPE PMK: Primary mouse keratinocytes PPARs: Peroxisome proliferator-activated receptors PPAR: Peroxisome proliferator-activated receptor PS: Phosphatidylserines p-STAT3: Phosphorylated signal transducer and activator of transcription 3 PUFA: Polyunsaturated fatty acid RANTES: Chemokine regulated upon activation normal T cell expressed and secreted RhoA: Ras homolog family member A ROS: Reactive oxygen species RTK: Receptor tyrosine kinase SM: Sphingomyelins SP: Sphingolipids sPLA2: Secretory phospholipase A2 TAG: Triacylglycerols tetranor PGEM: 8-[(1R,2R,5R)-2-(2-carboxyethyl)-5-hydroxy-3-oxocyclopentyl]-6-oxooctanoic acid TGF-: Transforming growth factor beta Th17: Lymphocytes Th17 Th22: Lymphocytes Th22 TNF-: Tumor necrosis factor TP: Thromboxane receptor TRPA1: Transient receptor potential cation channel, subfamily A, member 1 TRPV1: Transient receptor potential cation channel subfamily V member 1 TrXA 3 : Trioxilin A3 TrXB 3 : Trioxilin B3 TSLP: Thymic stromal lymphopoietin TXA 2 : Thromboxane A2 TXB 2 : Thromboxane B2 TXS: Thromboxane synthase UV: Ultraviolet vLPR: Very late-phase References Lee H-J, Kim M

Bacterial tyrosinases

Increased total neurite length relative to vehicle-treated db/db mice

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