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Treatment with ACEIs or ARBs reduces EGR1 expression in glomeruli, inhibits renin expression, decreases secretion of TNF-a and fibronectin proteins (FN) from tethered cells, slows tethered cell injury, and affects the behavior of MCs [75]

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Researchers never published the full results, although a short write-up in 2005 reported that the second trial found a positive effect but that it didnt reach statistical significance

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