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Of note, as a conventional treatment in SLE, corticosteroids, particularly when used at high doses or prolonged duration, leads to adverse events such as immunosuppression and dyslipidemia

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This observation is consistent with previous findings showing that UFMylation of PD-1 in T cells stabilizes the protein by preventing its ubiquitination, and that inhibition of UFMylation via UFL1 knockout reduces PD-1 levels, enhancing T cell-mediated anti-tumor immunity

Theres no optical viewfinder on the PowerShot SD940 Digital ELPH, in case you hadnt noticed