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DSIP appears to exert action on some regions of the brain that regulate sleep, primarily the hypothalamus and brainstem, by binding to certain receptors responsible for them

Experimental studies have reported: reduced adiposity improved insulin sensitivity increased energy expenditure favorable metabolic changes However: these findings have not yet been confirmed by large human trials

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NaBPC157 (10 g or 10 ng/kg b.w., i.p., i.g.) was given prophylactically 1 hour before ligation, whereas the therapy was conducted by a daily application 1 day after ligation (last application 24 hours before sacrifice)