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Furthermore, zinc is a cofactor for HDACs, which remove acetyl groups from histone proteins, resulting in condensed chromatin and gene silencing

DHA is heavily concentrated in the brain and preferentially taken up over other fatty acids

doi: 10.1016/S1474-4422(14)70148-6 27 MangoDBonito-OlivaALedonneACappellacciLPetrelliRNisticoRet al

In individuals with confirmed B12 deficiency, correction may help normalise homocysteine metabolism, as deficiency has been associated with elevated homocysteine levels