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As GR might gain access to many of its genomic targets via interacting with FOXA1, 84 we examined FOXA1 ChIP-seq data and found that FOXA1 bound to several ARBSs (around ARBS4-7) of the BCL-2 region in VCaP cells cultured in CDSS for 24 h or 48 h but not in VCaP_Enza-3w cells (supplementary Fig

Vitamin C acts as an antioxidant to support healthy proteins in the lens and is linked with lower incidence of cataract development

Niacinamide (Vitamin B3): Helps strengthen the skin barrier, reduce inflammation, tighten pores, and even out skin tone

For example, renal endothelial cells (critical for maintaining microvascular integrity) or mesangial cells may also undergo ferroptosis in response to contrast agents, yet their role in amplifying CIN injury (e.g., via paracrine signaling or microvascular rarefaction) has not been rigorously characterized