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Phenotypes result from the expression of an organisms genes as well as the influence of environmental factors and interactions between the two Executive summary The ability to conduct validated analyses of small molecule (steroids, lipids, folates, glutathione and other thiols, glutathione adducts and their metabolites and DNA adducts) and protein biomarkers is critically important in order to establish their sensitivity and specificity for identifying particular diseases

PDs produce a dysbiosis of the oral microbiome leading to an exaggerated immune response by the host and, consequently, destruction of dental supporting tissues

PMCID: PMC11101738.10.1016/j.ekir.2024.01.002 [PMC free article: PMC11101738] [PubMed: 38765600] [CrossRef] 17