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Among oral immunosuppressive drugs, the most frequently administered was azathioprine (57.7%), followed by mycophenolate mofetil (26.8%) (Table 4)

This approach delivers the peptide directly into the joint space, concentrating its effects at the site of cartilage damage, synovial inflammation, or tendon injury within the joint, rather than relying on systemic diffusion from a subcutaneous injection site

Utilizing this database, we endeavored to predict the drugs that may target the key DEGs in the granulosa cells of PCOS patients and conducted visualization to facilitate subsequent correlation analyses

The substrate binding by the SBD is implemented in two steps: after binding to the client protein via SBD-, HSP70s trap it by closing SBD-, serving as a cap or lid (Wang et al., 1998