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for example, What are the hallmarks of neurodegeneration during COVID-19 infection? and Are epigenetics promising solution against post-COVID-19 neurodegeneration? In addition, nano-formulas might be a better novel treatment for COVID-19 neurological complications, which raises one more question, What are the challenges of nano-bio-based nanocarriers pre- or post-COVID-19 infection? especially in the light of omics-based changes/challenges, research, and clinical practice in the framework of predictive preventive personalized medicine (PPPM / 3P medicine)

doi: 10.1038/ncomms7051 275 MaharajKPowersJJMediavilla-VarelaMAchilleAGamalWQuayleSet al

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It is commonly applied as a fixative in microscopy and preservation methods for cell enumeration 48,49