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Deng Q, Yu X, Xiao L et al (2013) Neoalbaconol induces energy depletion and multiple cell death in cancer cells by targeting PDK1-PI3-K/Akt signaling pathway

We first assessed the expression of REST in different organs and found moderate expression in the heart, liver, spleen, lung, and kidney, as well as lower levels in the brain (Supplemental Figure 1, A and B

Studies suggest oral bioavailability ranges from 3-30% depending on formulation, with liposomal preparations showing improved absorption compared to standard capsules