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For the intracellular metabolomic analysis, cells were quickly washed for three times with PBS to remove contaminations from the media

Studies suggest that peptides purchased from online sources can have substantial impurities and contaminants

-Tocopherol was also linked to lower NFT accumulation in brain regions affected in early Braak stages, such as the hippocampus, amygdala, and entorhinal cortex but not in the later-affected brain regions [12] In APOE4 carriers (i.e., individuals with at least one copy of the 4 allele of the apolipoprotein E (APOE) gene, a well-established genetic risk factor for late-onset AD), higher dietary intake of -tocopherol was significantly associated with a slower rate of cognitive decline [46]

A cohort study from the Nurses Health Study II reinforced these findings, showing that higher total fibre intake was associated with a decreased incidence of GERD symptoms, with the strongest associations observed for fibre from fruits and vegetables, but not from cereals (Reference Samuthpongtorn, Mehta and Ma78)