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Los niveles elevados de OE en monarcas adultas se han relacionado con un menor xito migratorio en la poblacin de monarcas orientales y con reducciones de la masa corporal, la esperanza de vida, el xito en el apareamiento y la capacidad de vuelo

There are three prevailing mechanisms involved: firstly, phosphorylation of the intracellular terminus of CD44 occurs following its interaction with HA and subsequent activation by protein kinase c (PKC) ( Figure 2 ) ( Figure 2 CD44 can synergistically interact with VLA-4 integrins through intracellular signaling pathways, aside from its significant adhesion role ( Lipid rafts are cholesterol- and sphingolipid-rich microstructural domains in the plasma membrane ( Paxillin, an adhesive patch adaptor protein, is mainly localized at focal adhesions (FAs) ( 2.2 Mechanisms involved in growth and proliferation survival CD44 is capable of binding to ligands to activate a range of intracellular signaling pathways that regulate cellular growth, proliferation, survival and various other activities

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