melanotic macule on lower lip Oral pathology: Noting a pigmented that often presents a diagnostic dilemma Freckle on Lip: Meaning, Causes

Freckle on Lip: Meaning, Causes and Is It Dangerous? (Labial Melanotic Macule) Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in Treatment of labial melanotic macules on the lip. These are benign spots that appear on the lips for no apparent reason. The causes are mostly genetic, but similar spots can appear in smokers, after Pigmented macular lip lesion Clinical Advisor

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