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10.1007/s00109-016-1488-y 46 HuangT.ZhangK.SunL.XueX.ZhangC.ShuZ.et al (2015)

This paper comprehensively reviews IRAK4 and its family members physiological functions, systematically examines the IRAK familys roles in the IL-1R/TLR pathway, with a focus on IRAK4, analyzes IRAK4s specific role in HS, strengthening the theoretical basis for using IRAK4-targeted drugs

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