l-glutamine glutathione L-Glutamine, 500 mg, 100 vegetarian capsules BESTVITE L-Glutathione 250mg (60 Vegetarian

Mark Zafereo is a Professor of Head and Neck Surgery at MD Anderson Cancer Center in Houston, Texas where he is Section Chief of Head and Neck Endocrine Surgery and Associate Medical Director of the Head & Neck Center

Glutathione, often referred to as the master antioxidant, is a tripeptide made up of glutamine, cysteine, and glycine

GSH and GSSG are also involved in many cellular processes termed S-glutathionylation where disulfide bonds are formed with protein Cys residues that subsequently alter enzymatic activity or protein function

3.2 Role of TGF- in radiation skin fibrosis TGF- is a cytokine intricately involved in the fibrotic process across various organs and tissues ( 3.2.1 TGF- Signaling and cellular mechanisms in radiation-induced fibrosis TGF- exerts its effects through the activation and proliferation of fibroblasts, leading to ECM accumulation ( TGF- expression is dose-dependent on radiation exposure, binding to its receptors to form a trimeric complex which can lead to tissue fibrosis ( Figure 2 )