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AOP: 492 Title Glutathione conjugation leading to reproductive dysfunction via oxidative stress Short name Graphical Representation Point of Contact Contributors Leonardo Vieira Coaches OECD Information Table This AOP was last modified on September 14, 2023 09:47 Abstract Here, an Adverse Outcome Pathway (AOP) is proposed for reproductive dysfunction via oxidative stress, which is motivated by the current understanding of the role of oxidative stress in reproductive disorders

CBS degrades into tetramers and dimers Though both full-length CBS constructs resulted in highly similar filament maps, one key difference was the observed protein degradation and the presence of slightly shorter oligomers of the CBS FL construct without a permanent His-tag (Supplementary Fig