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IV use at appropriate infusion rates has not shown the same risk profile, but medical history review is standard Individuals with a known sensitivity to sulfur-containing compounds should inform their provider High-dose IV glutathione for cosmetic skin lightening, particularly in unregulated settings, has been associated with adverse events including anaphylaxis and reports of hepatotoxicity

Race and liver mass Some studies have found differences between races in the rate of alcohol elimination from the body, and have posited that liver mass may be a correlating explanation for these differences

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Swab the top of the vial with alcohol before insertion of the needle to ensure sterility