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Animal studies have demonstrated that continuous administration of IGF-1 can prevent cartilage degradation and promote repair, highlighting its potential as a treatment for osteoarthritis (Wen et al., 2021)

This suggests that NO and hydrogen peroxide produced by mtNOS act as diffusible toxohormones, promoting oxidative stress in nearby non-tumor tissues and thereby facilitating tumor progression

The researchers found that the neurotransmitter norepinephrine, which activates the fight-or-flight stress response, was the link between emotional stress and gray hair

Transverse descriptive study of xenobiotic exposures in patients with chronic pancreatitis and pancreatic cancer