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Description

Under basal conditions, Nrf2 is sequestered in the cytoplasm by Kelch-like ECH-associated protein 1 (Keap1), which targets it for ubiquitin-mediated degradation

Strategies include staying hydrated, getting plenty of sleep, eating a good breakfast, drinking in moderation, limiting high congener drinks, and taking certain supplements or medications

Frequently used to increase memory, focus, creativity, intelligence, and motivation

Data have suggested this occurred through modulation of transforming growth factor beta (TGF-) pathway proteins, specifically mothers against decapentaplegic homolog 3 (Smad3)