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Two groups were defined: 60 children with Down syndrome and 29 siblings without Down syndrome

These data revealed that cytotoxic chemotherapeutic agents with different mechanisms of action, including taxanes and platinum-containing compounds, can trigger senescence of normal and malignant cells in different tissues in vivo that may worsen prognosis of the disease

Potential considerations include: Mild Skin Irritation As with many skincare ingredients, some individuals may experience: Temporary redness Mild irritation Sensitivity Dryness Patch testing is often recommended before regular use