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doi: 10.3389/fnagi.2022.870517 28 CobyAJPicardalFShelobolinaEXuHRodenEE

Chamoun K, Kantarjian H, Atallah R, Gonzalez GN, Issa GC, Rios MB, Garcia-Manero G, Borthakur G , Ravandi F, Jain N, Daver N, Konopleva M, DiNardo CD, Kadia T, Pemmaraju N, Jabbour E, Cortes J

Shes a triple agonist targeting GLP-1, GIP, and glucagon receptors simultaneously

Elevated systemic oxidative stress can lead to notable fibrinogen oxidation and structural alterations, which are associated with impaired fibrin polymerization and enhanced resistance to plasmin-induced lysis