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For example, curcumin has been evaluated in Phase II clinical studies in pancreatic cancer and colorectal cancer patients, where oral doses up to 8 g/day demonstrated acceptable safety but limited systemic exposure, highlighting pharmacokinetic challenges

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Patients should review all their medications with their healthcare provider, as concomitant medicines (including SGLT2 inhibitors, diuretics, or caffeine-containing products) may contribute to increased urination