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Potential clinical signs include: Vomiting (more than twice a month) Diarrhea (lasting more than three weeks or intermittently over one month or more) Weight loss The inflammation is suspected to be caused by an overreaction of the immune system to intestinal contents that are usually well-tolerated, such as certain foods or normal bacteria, and tends to improve in response to diet changes, antibiotics, or steroids

doi: 10.1016/j.yebeh.2016.11.016

Further investigation during following studies confirmed a 3.7-fold lower HER-2/neu mRNA expression in FVB/N female mice compared to controls [68]

Consistent with this, our previous study demonstrated that high energy intake during late gestation resulted in increased MDA accumulation in sows (6)