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Ca 2+ signaling, mitochondria and cell death

To further validate our cell line data in primary cells we have performed bystander death of immature primary neurons in exposure to SA exposed primary microglia supernatant

Since the latter study had a placebo group which had redox and methylation biomarkers measured at the beginning and end of the intervention, we use this placebo group as a control group for all three studies in order to determine if the changes in redox and methylation metabolism were significant as a result of the three interventions