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Experimental investigations have extensively utilized GSH for studies of redox biology, thiol chemistry, enzyme-cofactor interactions, glutathione-dependent regulatory networks, and signal transduction mechanisms involving sulfur-containing biomolecules

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The following sections examine the available evidence on molecular mechanisms of thiamine transport, metabolism, and function in the gastrointestinal system, offering insights for the interpretation of medical studies on thiamine-responsive gastrointestinal disorders that highlight mechanistic connections between common disorders of gastrointestinal tract and TD

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