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[212] The T102C polymorphism has also been studied in relation to suicide attempts, with a study finding excess of the C/C genotype among the suicide attempters

This molecular pathway may be influenced by the level of daily physical activity, as a study using high-throughput sequencing found that physically fit individuals had higher fecal butyrate levels, better VO2 max values, more diverse gut microbiota, lower LPS biosynthesis, and consequently, less systemic inflammation [22, 44]