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In the European Union, it is also known under the E number E955

Once the drug is present on the skin surface, it can diffuse through the epidermis through two routes, either transepidermal(transcellular or intercellular) or transappendageal(sweat ducts, hair follicles, and pilosebaceous glands) [311]

Mehmood SS, Lu G, Luo D et al (2021) Integrated analysis of transcriptomics and proteomics provides insights into the molecular regulation of cold response in Brassica napus