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Description

Researchers examine how NNMT inhibition affects NAD+ levels, sirtuin activity, mitochondrial efficiency, glucose/lipid metabolism, and metabolic parameters in experimental systems focused on aging and metabolic disorders

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Minzasolmin (UCB0599), a single enantiomer of NPT200-11, is an orally bioavailable small molecule that inhibits the early stages of -syn misfolding, thereby preventing pathological -syn aggregation [153]