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There were no significant differences in gender, age, smoking status, history of diabetes mellitus, and use of medications between the two groups at baseline

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Common early symptoms may include: Headache Flushing or warmth Mild dizziness Nausea Drowsiness Fatigue These effects are generally considered temporary and are often related to the body adapting to increased growth hormone signaling and changes in IGF-1 activity

however, it was not directly utilized for growth and proliferation as indicated by Ki67 staining in melanoma tumours