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8 Cells primarily catalyze the reduction of lipid peroxides through two antioxidant systems including the glutathione (GSH)/glutathione peroxidase 4 (GPX4) system and the coenzyme Q10 (CoQ10)/ferroptosis suppressor protein 1 (FSP1) system

The latter could contribute to research in the development of therapeutic approaches and understanding tissue resiliency and wound healing processes

The Journal of Clinical Investigation 56 (5): 11251131

Other cytokines, such as fibroblast growth factor (FGF) and hepatocyte growth factor (HGF), also act after inducing ROS, and ROS itself may affect growth factor receptor signaling, further promoting tumor development 63