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However, some factors such as Olig1/2, NKx2.2, and (SRY-Box transcription factor 10) Sox10 are persistently present throughout oligodendrocyte maturation (Kang and Yao, 2019)

Therefore, the use of mice with inducible double knockout for Jnk1/Jnk2 may be a valuable approach to address the role of JNK in APAP-mediated hepatotoxicity