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developed a dual pH-responsive hydrogel cross-linked with a tumor acidity neutralizer (mesoporous bioactive glass nanoparticles) and a NET lyase (deoxyribonuclease I, DNase I), and used it in combination with NK infusion to prevent postoperative tumor recurrence (Figure 7) ( FIGURE 7 In addition, more and more evidence show that LDDS can be tailored according to the patients condition to promote personalized tumor treatment (Lu Y

CD38 as a target of IB4 mAb carrying saporin-S6: design of an immunotoxin for ex vivo depletion of hematological CD38+ neoplasia