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95 % CI (012, 033), P = 0365) (online Supplementary Fig

Previous studies have reported that BAs can exacerbate skin inflammation by activating G-protein bile acid-coupled receptor 5 (TGR5) and sphingosine-1-phosphate (S1P) receptor 2 (S1PR2) in the skin ( Escherichia-Shigella may facilitate the onset and progression of PSO by inhibiting apoptosis through the BAs metabolic pathway