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Physicians may opt to treat these patients and monitor for improvement of metabolic markers, particularly in populations at high risk of clinical vitamin B 12 deficiency, or observe these patients and periodically reassess their levels of vitamin B 12 , homocysteine, and/or methylmalonic acid

Biochem Pharmacol 63:30520, PMID: 11841806 Haddad JJ (2011) A redox microenvironment is essential for MAPK-dependent secretion of pro-inflammatory cytokines: modulation by glutathione (GSH/GSSG) biosynthesis and equilibrium in the alveolar epithelium

The solubilizing effect of ATP is dependent upon the adenosine moiety The recognition that ATP may facilitate the transition of a droplet into a fibril and back into a droplet [285, 290] supports previous computational and experimental studies that showed that at physiological levels between 0.5 mM to 10 mM, ATP prevents A misfolding via stabilization through the triphosphate moiety and the solubilizing effect of the adenosine moiety [291]

These analyses have not been adjusted for multiple comparisons and are excluded from formal hypothesis testing