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To the extent a fund acquires shares of its Underlying ETFs in connection with creations and during reallocation, the fund typically will not acquire Underlying ETF shares on the first day of the target outcome period defined in the Underlying Funds prospectus (Target Outcome Period)

ATOX1 bound Cu + can also be transferred to other cytosolic enzymes requiring Cu + as well as metallothionein, a cysteine rich protein which can store to a certain extent excessive Cu + ( Figure 1 ) (24-26)

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