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Limitations include relatively short treatment periods (6 weeks per arm), potential carryover effects despite washout, modest sample size limiting power for subgroup analyses and exclusion of newer agents (e.g., tapentadol) and long-term safety outcomes, which may restrict applicability to broader clinical practice

Chen Y, Wang Y, Chen J, Chen X, Cao W, Chen S, et al

Many advanced hair formulations include both peptides for complementary benefits

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