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Remarkably, elevated LC3B-II/I ratios and increased p62 levels were observed in VDAC1 knockdown AGSR cells compared to the control group ( Figure 4E )

We and others have reported that GSH depletion in antigen presenting cells inhibits Th1-related cytokine production like IFN- and IL-12, which supports Th2- mediated humoral immune response in SLE patients [39]

Giannetti, E., Maglione, M., Alessandrella, A., Strisciuglio, C., De Giovanni, D., Campanozzi, A., Miele, E., & Staiano, A

There was diversity observed in intestinal microbiota amongst subjects with hepatitis B virus-related cirrhosis and subjects with chronic hepatitis B (160, 161)