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Excess abdominal fat is associated with higher inflammation and increased risk of insulin resistance, high blood pressure, and cardiovascular disease, which is why many menopausal women consider GLP-1 medications as part of a broader, clinician-guided weight management plan

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8 GIPR deficiency in mice leads to impaired glucose tolerance with reduced cell function, 9 while GIP overexpression results in improved glucose tolerance, enhanced cell function, and resistance to highfat dietinduced obesity

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