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Many nanotechnology-based delivery systems are still in the proof-of-concept stage, even for drugs that are already approved for human use via other routes (or vehicles based on materials already approved for other uses)

Cells were then washed three times with ice-cold uptake buffer and lysed in 500 L 0.1 M NaOH

This extraordinary recycling efficiency is why PQQs antioxidant protection is measurable at microgram doses (dietary intake is only 0.1-1 mcg/day from food) rather than the milligram or gram doses required for vitamin C

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