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This variant has exhibited the most completely reduced intermediate spectrum of SmTGR yet observed, with approximately 90% of the FAD being reduced (based on an assumed extinction coefficient change of 9000 M -1 cm 1 ), with limiting NADPH concentration

Conclusions GSH is a key thiol antioxidant in the human body which, among its many functions, serves as a major mitochondrial protector, and through this function is linked to many chronic illnesses which make up the bulk of the healthcare burden in Western societies today

At the specialist evaluation stage, diagnosis could be refined in memory clinics or neurology departments using more specific ferroptosis biomarkers