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Damaged intestinal barrier can facilitate the development of local diseases such as irritable bowel disease, inflammatory bowel disease or celiac disease, but also the development of systemic inflammatory diseases such as rheumatoid arthritis, ankylosing spondylitis, hepatitis, and lupus erythematosus, neurodegenerative or psychiatric conditions, or metabolic diseases such as diabetes or obesity

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Following compression injury, however, microglial processes often extend through the glial limitans into the injured meningeal space (white arrows) as evidenced by the presence of microglial processes adjacent to the skull bone (blue)

The Journal of Neuroscience Research 2010