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In view of the structure and composition, the constructed siRNA delivery nanosystem is called siRNA-encapsulated and aptamer-incorporated core/shell (CS) nanoparticle (siRNA/Ap-CS) that exhibits high serum stability, tumor-specific targeting ability, long circulation lifetime and controlled siRNA release in endogenous miRNA-responsive fashion

Material and methods Search engine The data collected for reviewing was by studying the published work from PubMed, Elsevier, Science direct, Medline and Google open access publications by searching keywords such as Aducanumab

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