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To empirically test this future hypothesis, long-term controlled trials may need to standardize the intervention by assigning either a probiotic or prebiotic regimen aimed at propionate enhancement to subjects with mild cognitive impairment

Treatment with 0.1% Camellia japonica extract led to notable enhancements in the clinical manifestations of dry eye, including increased tear production and diminished inflammation, with a substantial reduction in inflammatory marker levels [74]

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In addition, the treatment with NP4 reduced the level of anti-inflammatory M2-type macrophages by 20% in comparison to the treatment with NP2 (Supplementary Fig