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Between baseline and follow-up, the subject's LDL-C increased from 90 to 321 mg/dL, the former measure being marked as optimal, and the latter, in alarming red, being twice the threshold of high-risk (Figure 1A)

[] compared such a drug, called Enclomiphene citrate, with testosterone replacement therapy (Androgel) in overweight men with low testosterone, or hypogonadism

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