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The injection of LPS provoked an elevation of plasma IL-6 concentration (from values below the lowest detectable standard in not-treated groups of animals to 6322.82 537.00 pg/mL in old LPS-treated rats and 7415.62 451.88 pg/mL in young LPS-treated rats)

"Stability of buffer-free freeze-dried formulations: a feasibility study of selected pharmaceutically relevant proteins." European Journal of Pharmaceutics and Biopharmaceutics