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Therefore, some of these findings would corroborate that UA may be a modifiable factor in the progression of chronic kidney disease, without sufficient data to state whether the beneficial effect of allopurinol is due to the reduction of UA or to the antioxidant effect produced by inhibiting the xanthine oxidase enzyme, however, the two large randomized clinical trials do not offer positive results so there is insufficient evidence to recommend allopurinol treatment in patients with asymptomatic hyperuricemia

Sumar helps patients uncover hidden imbalances that standard medical tests often miss

Monosodium l-glutamate and dietary fat exert opposite effects on the proximal and distal intestinal health in growing pigs

Yang D, Wang X, Zhang L et al (2022) Lipid metabolism and storage in neuroglia: role in brain development and neurodegenerative diseases