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By secreting growth factors and extracellular matrix proteins, MenSCs contribute to reconstructing the bone marrow microenvironment and support the ex vivo expansion of hematopoietic stem cells (Khoury et al., 2011)

Overexpression of miR-485-5p reverses this effect, confirming the functional specificity of this regulatory axis

Hesperidin improved endothelial function, reduced CRP levels by 32%, and decreased levels of total cholesterol, ApoB, and markers of vascular inflammation, relative to placebo