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Future studies should investigate whether HSL-driven metabolic reprogramming also influences the surface localization and clustering of these receptors, as well as the downstream signaling cascades initiated upon binding to apoptotic cells

If a patient has a particularly high-risk thrombophilia (for example, antiphospholipid syndrome with prior arterial clots, or recurrent unprovoked VTE), a discussion with their physician is needed to decide if fasting is safe or if temporary prophylactic measures are warranted

If the patients concern involves growth hormone or IGF-1 signaling, body composition, or another endocrine issue, the evaluation is different again

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